Do you want to find a row/cell by some data value and highlight that cell? In other words, find a row where Col1 = 'some value' and then locate column x and highlight it?
You can use the Find method of a DataView to get a row by index. If you just need a reference to the Row and Column (and not in particular where that value is in the grid), you can use the DataTable's Select method which returns a DataRow array.
-Ner