The sender argument will be the button that was clicked
the folowing code will just display hte name of the button clicked - you could use this in a select case statement if you needed to make a decision based on this.
Private Sub Button2_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button2.Click, Button1.Click, Button3.Click
Dim b As Button
b = DirectCast(sender, Button)
MessageBox.Show(b.Name)
End Sub